Atarax 25 mg in Sutton Coldfield

Atarax 25 mg in Sutton Coldfield

4.65 out of 5


Active Ingredient: Hydroxyzine

  • type: pill
  • Quantity in a package: 60 pieces
  • Functionality: Antidepressant
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  • Chemical name: Atarax
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    A randomised double-blind placebo controlled study was conducted by Nettis et al. This study demonstrated greater benefit with the combination of desloratadine plus montelukast compared to desloratadine alone in improving pruritus, number and size of weals, quality of life, and VAS.


    Improvement in the number of separate urticarial episodes did not show a significant difference between the two groups.

    There were no significant clinical, biochemical or electrocardiographic adverse effects seen with LTRA use.

    The study was well conducted and risk of bias was low, with clear details of blinding and minimal loss to follow-up.

    Wan et al.


    The drop out rate among those receiving placebo was high, as the patients did not experience benefit 13 out of 30. UAS and a visual analog scale were used to evaluate outcome. The efficacy of the combination of antihistamine and LTRA was comparable with treatment with dual antihistamine therapy, and superior to placebo.

    The main difficulty in interpreting this study from a clinical perspective is that the comparison was with dual antihistamine therapy. Leukotriene antagonist vs.


    The study by Di Lorenzo et al. Similarly, on instantaneous evaluation of interference with sleep and the use of rescue medication, desloratadine was shown to be superior to montelukast, although this benefit was not demonstrated with regards to interference with daily activities.

    Nettis et al. The total symptom score was worse in the fexofenadine group compared with the montelukast group.

    However the reduction in time of symptomatic profile was the same in both groups. Godse compared montelukast with cetrizine in patients with CIU, in a randomised trial of 20 patients.


    The outcome measure was improvement in UAS and severity of itching at one week and two weeks after commencing therapy. Results with montelukast were disappointing, with 8 of the 10 patients in the montelukast group reporting worsening of itching and an increase in the UAS; 2 patients were lost to follow-up.

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